We are having an issue with some of our servers after updating some custom DLLs (DLLs doesn't go the GAC, just fully trusted location). We have multiple versions of our application in the same server. The older version seems to run fine without error. The newer version with the updated custom DLLs does.
Our application will sometimes throw a System.IO.FileLoadException with no reference to the file it is trying to load. The problem doesn't happen all the time. Normally, after a reboot the error goes away. However, there are some users that report seeing the error later in the week. We have a server that was experiencing the error in the morning but later that day no more incidents.
Basically, the error clears up after a reboot of the server or just clears up on it's own. Any ideas?
Windows Server 2008 R2